drugset / Trial / NCT07164313

A Study of ZW251 in Participants With Advanced Solid Tumors

NCT07164313 ↗

Phase 1 Recruiting 100 enrolled Zymeworks BC Inc.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to find out if ZW251, an antibody-drug conjugate targeting glypican-3 (GPC3), is safe and can treat participants with advanced cancers, including hepatocellular carcinoma (HCC), squamous cell non-small cell lung cancer (NSCLC), or germ cell tumors (GCT).

Timeline

Start
2025-10-21
Primary completion
2027-09
Completion
2028-05

Drugs

EvaluationDrugModalityDoseRoute
Subject ZW251 Unknown — Intravenous