drugset / Trial / NCT07164443

A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT07164443 ↗

Phase 3 Recruiting 1203 enrolled Janssen Research & Development, LLC
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the overall survival (length of time from the start of study to date of death from any cause) for pasritamig (JNJ-78278343) in Part 1 in combination with best supportive care (BSC) and in Part 2 with JNJ-87189401+BSC as compared to placebo with BSC in participants with metastatic castration-resistant prostate cancer (mCRPC; a stage of cancer that has spread beyond the prostate gland and is no longer responding to hormone therapies).

Timeline

Start
2025-09-02
Primary completion
2028-08-18
Completion
2028-08-18

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-87189401 Other / unclassified — —
Subject Pasritamig Other / unclassified — Intravenous