drugset / Trial / NCT07172022

A Study to Evaluate Crovalimab in People With Antiphospholipid Syndrome (APS)

NCT07172022 ↗

Phase 2 Withdrawn Hoffmann-La Roche
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The main purpose of this study is to evaluate the efficacy of crovalimab compared with placebo as an add-on therapy to vitamin K antagonist (VKA) in participants with APS.

Timeline

Start
2026-03-16
Primary completion
2030-03-11
Completion
2030-12-02

Outcome

Outcome not reported

Stopped (Business): “The study was discontinued due to a strategic business/portfolio decision by the sponsor and was not related to any medical or safety issue.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Crovalimab Monoclonal antibody 680 mg Subcutaneous
Subject Crovalimab Monoclonal antibody 1020 mg Subcutaneous