drugset / Trial / NCT07174375

PCSK9 Inhibitors in Acute Ischemic Stroke Patients Undergoing Endovascular Therapy

NCT07174375

Phase 2/3 Not yet recruiting 478 enrolled Nanfang Hospital, Southern Medical University
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, multicenter, randomized controlled clinical study to evaluate the efficacy of PCSK9 inhibitor in addition to standard therapy in patients with acute ischemic stroke undergoing endovascular therapy.

Timeline

Start
2025-09-15
Primary completion
2027-12-15
Completion
2027-12-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Alirocumab Monoclonal antibody 150 mg Subcutaneous
Subject Evolocumab Monoclonal antibody 420 mg Subcutaneous

Indications