Methylprednisolone Sodium Succinate With Endovascular ThRombectomy for Large Ischemic STroke

Summary

It is uncertain whether intravenous methylprednisolone improves outcomes for acute anterior circulation large vessel occlusion (LVO) patients with a large infarct core. In this study, the investigators hypothesize that methylprednisolone plus endovascular thrombectomy (EVT) might be superior to EVT alone in patients with evidence of a large infarct volume. The primary objective of the study is to establish the efficacy of methylprednisolone with EVT in patients with acute anterior circulation LVO and a large infarct core.

Timeline

Start

2025-10

Primary completion

2028-12

Completion

2029-12

Drugs

Indications