drugset / Trial / NCT07177859

A Phase III Study of NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients

NCT07177859

Phase 3 Not yet recruiting 78 enrolled Nanjing Chia-tai Tianqing Pharmaceutical
RandomizedParallel-groupOpen-labelTreatment

Summary

NTQ5082 capsules are a small molecule CFB inhibitor. This study is a multicenter, randomized, open-label, active-controlled Phase III clinical trial designed to evaluate the efficacy and safety of NTQ5082 capsules in the treatment of patients with paroxysmal nocturnal hemoglobinuria.

Timeline

Start
2025-11
Primary completion
2026-11
Completion
2026-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Eculizumab Monoclonal antibody
Subject NTQ5082 Small molecule 200 mg