drugset / Trial / NCT07180979

PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty

NCT07180979 ↗

Phase 4 Recruiting 90 enrolled Poznan University of Medical Sciences
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of this clinical trial is to evaluate whether different types of regional anesthesia can improve pain control and functional recovery after total hip arthroplasty in adult patients undergoing elective hip replacement surgery. The main questions it aims to answer are: Does the PENG block reduce opioid use in the first 48 hours after surgery more effectively than the combined L-ESPB + S-ESPB technique? Which method provides better pain relief, preserves muscle strength, and supports earlier mobilization? Researchers will compare the Pericapsular Nerve Group (PENG) block with the combination of Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB + S-ESPB) to see which provides better pain control, fewer side effects, and faster recovery. Participants will: Be randomly assigned to receive one of the two types of ultrasound-guided regional anesthesia Undergo standard hip replacement surgery under spinal anesthesia Be monitored for pain scores, opioid use, time to first walking, muscle strength, satisfaction, and side effects over the first 48 hours after surgery.

Timeline

Start
2025-09-15
Primary completion
2026-09-30
Completion
2026-11-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified 0.2 % Intrathecal
Comparator Ropivacaine Other / unclassified 0.5 % Intrathecal
Comparator Ropivacaine Other / unclassified 5 ml Intrathecal
Comparator Ropivacaine Other / unclassified 10 mg Intrathecal
Comparator Ropivacaine Other / unclassified 15 mg Intrathecal
Comparator Ropivacaine Other / unclassified 20 ml Intrathecal

Indications