drugset / Trial / NCT07185477

A Single-arm Single-center Trial of Bridging GPRC5D/CD3 Bispecific Antibody Treatment With BCMA CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma

NCT07185477

Phase 0 Not yet recruiting 20 enrolled Institute of Hematology & Blood Diseases Hospital, China
NaSingle-groupOpen-labelTreatment

Summary

This study is a prospective, single-arm, multicenter trial designed to evaluate the hematologic response rate and safety of GPRC5D/CD3 bispecific antibody bridging therapy prior to CAR-T cell infusion in patients with relapsed/refractory multiple myeloma (RRMM).

Timeline

Start
2025-09-15
Primary completion
2027-05-31
Completion
2028-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject QLS32015 Unknown