drugset / Trial / NCT07186101

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

NCT07186101

Phase 2 Recruiting 252 enrolled Eli Lilly and Company
RandomizedParallel-groupDouble-blindTreatment

Summary

The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with moderately to severely active ulcerative colitis (UC). Study participation will last approximately 118 weeks, including 104 weeks of treatment and may include up to 21 visits.

Timeline

Start
2025-11-10
Primary completion
2027-05
Completion
2029-03

Drugs

EvaluationDrugModalityDoseRoute
Subject LY4268989 Unknown Oral
Background Mirikizumab Monoclonal antibody Intravenous

Indications