drugset / Trial / NCT07187973

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

NCT07187973 ↗

Phase 1 Recruiting 24 enrolled Disc Medicine, Inc
NaSequentialOpen-labelTreatment

Summary

This is an open-label, multicenter, within-participant dose-escalation study examining up to 3 dose levels of DISC-3405 and will assess the safety, tolerability, PK, and PD of DISC 3405 in participants with sickle cell disease.

Timeline

Start
2026-01-06
Primary completion
2027-06
Completion
2027-10

Drugs

EvaluationDrugModalityDoseRoute
Subject DISC-3405 Unknown — Subcutaneous

Indications