drugset / Trial / NCT07193511

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

NCT07193511 ↗

Phase 1/2 Recruiting 355 enrolled Avenzo Therapeutics, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This study, the first clinical trial of AVZO-103, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity of AVZO-103 when administered intravenously as a monotherapy and in combination therapy to patients with locally advanced or metastatic urothelial cancer or other solid tumors.

Timeline

Start
2025-10-02
Primary completion
2030-03
Completion
2030-09

Drugs

EvaluationDrugModalityDoseRoute
Subject AVZO-103 Unknown — Intravenous