drugset / Trial / NCT07197762

MenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults

NCT07197762

Phase 4 Recruiting 125 enrolled Emory University Pfizer · collab
RandomizedParallel-groupOpen-labelPrevention

Summary

The goal of this clinical trial is to determine the immunogenicity of certain vaccines in protecting against meningitis B (MenB) in young adults who have previously received a different MenB vaccine. The main questions it aims to answer are: * How many participants are protected against four key types of MenB bacteria before and after getting the new vaccine? * How strong is the immune response after vaccination, and how many people show a noticeable boost in immune response?

Timeline

Start
2025-11-04
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject PENBRAYA Vaccine 20 ug Intramuscular
Subject PENBRAYA Vaccine 44 ug Intramuscular
Subject PENBRAYA Vaccine 120 ug Intramuscular
Subject PENBRAYA Vaccine 0.5 ml Intramuscular
Subject Trumenba Vaccine 120 ug Intramuscular
Subject Trumenba Vaccine 0.5 ml Intramuscular