drugset / Trial / NCT07198139

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CDI-988 in Healthy Adults After Challenge With Snow Mountain Virus

NCT07198139 ↗

Phase 1/2 Recruiting 40 enrolled Cocrystal Pharma, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Participants in this study will be given either CDI-988 or placebo orally before receiving a norovirus challenge virus and continuing for 5 days. Participants will not know whether they are getting placebo or CDI-988. The study will evaluate how well CDI-988 compared to placebo can reduce the incidence of clinical symptoms after a challenge with norovirus. The amount of virus in stool samples will be measured over time. Side effects and pharmacokinetics (the amount of CDI-988 in blood) will also be measured.

Timeline

Start
2026-03-01
Primary completion
2026-10-01
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CDI-988 Unknown — Oral