drugset / Trial / NCT07199855

Blinatumomab Combined With Venetoclax as Maintenance Therapy After Allo-HSCT in High-risk Ph Negative Acute B-cell Lymphoblastic Leukemia

NCT07199855

Phase 2 Active not recruiting 24 enrolled Zhejiang University
NaSingle-groupOpen-labelTreatment

Summary

This study is a single-center, single-arm, prospective clinical trial evaluating the efficacy and safety of blinatumomab combined with venetoclax as maintenance therapy for high-risk Philadelphia chromosome-negative acute B-cell lymphoblastic leukemia (B-ALL) after allogeneic hematopoietic stem cell transplantation .

Timeline

Start
2025-06-01
Primary completion
2027-06-01
Completion
2029-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Blinatumomab Monoclonal antibody
Subject Venetoclax Small molecule