drugset / Trial / NCT07199894

Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE

NCT07199894

Phase 3 Recruiting 120 enrolled Mansoura University
RandomizedParallel-groupSingle-blindTreatment

Summary

The goal of this clinical trial is to compare combination of Solifenacin and MIrabegron in treatment of primary mono-symptomatic nocturnal enuresis in children. It will also learn about the safety of that combination. The main questions it aims to answer are: Does combination of Solifenacin and MIrabegron lower the number of wet nights? What medical problems do participants have when taking combination of Solifenacin and MIrabegron? Researchers will compare the combination to omegapress to see if the combination works better to treat primary mono-symptomatic nocturnal enuresis. Participants will: Take the combination or Omegapress every day for 3 months Visit the clinic once monthly for checkups and tests Keep a diary of their symptoms and the number of wet nights

Timeline

Start
2024-12-01
Primary completion
2025-12-01
Completion
2026-02-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Desmopressin Peptide
Subject Mirabegron Other / unclassified
Subject Solifenacin Small molecule

Indications