drugset / Trial / NCT07202832

Urine Alkalinization for UTI in Women: RCT

NCT07202832

Not yet recruiting 50 enrolled Assiut University
RandomizedParallel-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate whether urinary alkalinization using potassium citrate can relieve symptoms and improve urine culture results in women aged 18 to 50 years with uncomplicated urinary tract infections (UTIs). The main questions it aims to answer are: Does urinary alkalinization reduce UTI symptom scores by Day 7? Does it lead to better urine culture results compared to antibiotic? Researchers will compare urinary alkalinization with potassium citrate to antibiotic to see if it provides more symptom relief and better microbiological outcomes. Participants will: Take either potassium citrate or antibiotic Be assessed for symptoms and adverse events on Day 7 Provide a urine sample for culture before and after treatment Report any return visits due to worsening symptoms or medication side effects

Timeline

Start
2025-10-15
Primary completion
2026-08-20
Completion
2027-01-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nitrofurantoin Unknown
Comparator POTASSIUM CITRATE ANHYDROUS Small molecule Oral