drugset / Trial / NCT07208240

Tb-PSMA-I&T Radionuclide Before Radical Prostatectomy in Patients With Locally Advanced Prostate Cancer - TbeforePROST Trial.

NCT07208240 ↗

Phase 1/2 Recruiting 20 enrolled Rabin Medical Center
NaSingle-groupOpen-labelTreatment

Summary

This is a multi-disciplinary collaboration between urologists, oncologists and nuclear medicine physicians from Beilinson hospital at Rabin Medical Center to address the major therapeutic challenge of locally advanced prostate cancer. Our aim is to evaluate the use of a novel treatment (Tb-PSMA) prior to the surgical removal of the prostate. This treatment has already shown initial promising results in patients with metastatic prostate cancer but has never been tested for locally advanced disease before surgery.

Timeline

Start
2025-08-12
Primary completion
2028-08-12
Completion
2028-08-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Tb-PSMA-I&T Unknown — —

Indications