drugset / Trial / NCT07212426
Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in PNH Patients.
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a multicenter, randomized, open-label, Phase II clinical study to evaluate the efficacy, safety, and pharmacokinetics of LP-005 injection in adult patients with paroxysmal nocturnal hemoglobinuria (PNH).
Timeline
- Start
- 2024-11-14
- Primary completion
- 2026-05-06
- Completion
- 2028-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LP-005 | Protein / enzyme biologic | 900 mg | Intravenous |
| Subject | LP-005 | Protein / enzyme biologic | 1200 mg | Intravenous |
| Subject | LP-005 | Protein / enzyme biologic | 1500 mg | Intravenous |