drugset / Trial / NCT07216794

Small Trial of Alendronate Impact on the Reservoir of HIV

NCT07216794

Phase 2 Not yet recruiting 30 enrolled National Institute of Allergy and Infectious Diseases (NIAID)
RandomizedParallel-groupDouble-blindTreatment

Summary

This clinical trial is designed to test the effects of alendronate (ALN) on people living with HIV who are already receiving antiretroviral therapy (ART). Participants are randomly assigned in a 2:1 ratio to either receive alendronate or a placebo, and neither the participants nor the researchers know who is receiving the actual treatment. The goal is to see if alendronate can reduce the size and activity of the HIV-1 reservoir in these individuals.

Timeline

Start
2026-06-27
Primary completion
2027-03-26
Completion
2027-05-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Alendronic Acid Small molecule 70 mg Oral