drugset / Trial / NCT07217171
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
Non-randomizedSequentialOpen-labelTreatment
Summary
The goal of this study is to evaluate the safety and effectiveness of EVOLVE104 in participants with advanced urothelial and squamous cell carcinomas who have previously taken standard treatment options, have declined or have been ineligible for treatment with these medications. Participants with advanced or metastatic cancer who meet all eligibility criteria may be eligible to participate in the study.
Timeline
- Start
- 2025-11-13
- Primary completion
- 2029-01-29
- Completion
- 2031-01-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | EVOLVE104 | Unknown | — | Intravenous |
Indications
anal squamous cell carcinoma
cervical squamous cell carcinoma
esophageal squamous cell carcinoma
skin squamous cell carcinoma
squamous cell carcinoma of penis
squamous cell lung carcinoma
tongue squamous cell carcinoma
urethra squamous cell carcinoma
urinary bladder cancer
vaginal squamous cell carcinoma
vulvar squamous cell carcinoma