drugset / Trial / NCT07219550

A Study of Calderasib (MK-1084) in Participants With Hepatic Impairment and Healthy Volunteers (MK-1084-017)

NCT07219550

Phase 1 Recruiting 58 enrolled Merck Sharp & Dohme LLC
NaSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to learn what happens to calderasib levels in a person's body over time. Researchers will measure what happens to calderasib levels in the body when it is given to participants with hepatic (liver) impairment and healthy participants. Researchers also want to learn about the safety of MK-1084 when it is given to people with hepatic impairment and if people with hepatic impairment can tolerate it.

Timeline

Start
2025-11-05
Primary completion
2026-08-07
Completion
2026-08-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Calderasib Unknown Oral

Indications

No indication recorded.