drugset / Trial / NCT07225842
The Bridging Antiplatelet Therapy With Cangrelor 2 Study
NaSingle-groupOpen-labelTreatment
Summary
The primary aim of this study is to determine rates of patients with optimal platelet reactivity range, defined as PRU levels between 85 and 208, when using a (PFT)-guided titration of cangrelor infusion rate (cangrelor titration) compared to 0.75 mcg/kg/min (standard-dose infusion) for bridging.
Timeline
- Start
- 2026-02-18
- Primary completion
- 2027-09
- Completion
- 2027-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cangrelor | Small molecule | 0.25 ug/kg | — |
| Subject | Cangrelor | Small molecule | 0.5 ug/kg | — |
| Subject | Cangrelor | Small molecule | 0.75 ug/kg | — |
| Subject | Cangrelor | Small molecule | 1 ug/kg | — |
| Subject | Cangrelor | Small molecule | 1.5 ug/kg | — |