drugset / Trial / NCT07227636

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

NCT07227636

RandomizedParallel-groupDouble-blindTreatment

Summary

The researchers are doing this study to find out whether the combination of botensilimab and balstilimab (BOT/BAL), followed by balstilimab alone, is an effective treatment for people with microsatellite stable (MSS) colorectal cancer or colorectal liver metastases (CRLM) who have measurable residual disease (MRD) after standard treatment with surgery and chemotherapy or total neoadjuvant therapy (TNT).

Timeline

Start
2025-11-07
Primary completion
2030-11
Completion
2030-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Balstilimab Monoclonal antibody Intravenous
Subject Botensilimab Monoclonal antibody Intravenous

Indications