drugset / Trial / NCT07228247

A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

NCT07228247 ↗

Phase 1/2 Recruiting 147 enrolled Hutchmed
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a first-in-human (FIH), phase Ⅰ/Ⅱa, open-label, multicenter clinical study of HMPL-A251 monotherapy in adult participants with unresectable, advanced or metastatic HER2-expressing solid tumors.

Timeline

Start
2025-12-16
Primary completion
2028-11-30
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject HMPL-A251 Unknown — Intravenous

Indications

No indication recorded.