drugset / Trial / NCT07231497

Cognitive Strategies in Early Psychosis 1

NCT07231497

NaSingle-groupOpen-labelBasic science

Summary

The goal of this clinical is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. The investigators will ask people who do not have psychosis to take a single dose of modafinil and then complete some brain games on the computer that measure decision making. They hope to improve our understanding of psychosis to help people in the future. The main research questions are: Does a single dose of modafinil change how people play the brain games? Does a single dose of modafinil change brain activity? Participants will: Complete an interview and self-report questionnaires. Complete safety screening activities, like a blood draw, a urine drug test, and an alcohol breathalyzer test. Take a single dose of modafinil. Complete brain games while wearing an electroencephalography (EEG) cap, before and after taking the single dose of modafinil. EEG measures electrical activity in the brain.

Timeline

Start
2025-10-31
Primary completion
2030-04-30
Completion
2030-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Modafinil Small molecule 200 mg

Indications

No indication recorded.