drugset / Trial / NCT07234942

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

NCT07234942 ↗

Phase 1 Recruiting 50 enrolled Hoffmann-La Roche
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study aims to evaluate the safety, tolerability, immunogenicity, pharmacokinetics, and pharmacodynamics following administration of RO7812653 in participants with eAD.

Timeline

Start
2026-01-27
Primary completion
2028-04-19
Completion
2030-03-05

Drugs

EvaluationDrugModalityDoseRoute
Subject RO7812653 Unknown — Intrathecal

Indications