drugset / Trial / NCT07237763

Assessment of the Efficacy of Topical Ketoconazole 2% Cream in Comparison With Topical Retinoids in the Treatment of Mild Comedonal and Papulopustular Acne

NCT07237763

Active not recruiting 52 enrolled Cairo University
RandomizedParallel-groupDouble-blindTreatment

Summary

objective: is to assess the efficacy of topical ketoconazole 2% cream in comparison with topical retinoid in the treatment of mild comedonal and papulopustular acne to determine if ketoconazole can be an alternative to topical retinoid with less side effects and more compliance. Patients and methods: 52 patients with mild comedonal and papulopustular acne will be randomized into 2 groups and instructed to apply randomly either topical KTZ 2% cream or topical retinoid cream for a period of 12 weeks. Evaluation of response will be done by a blinded investigator

Timeline

Start
2024-01-15
Primary completion
2025-12
Completion
2025-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Adapalene Other / unclassified 2 % Topical
Comparator Ketoconazole Small molecule 2 % Topical

Indications