drugset / Trial / NCT07238075

ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers

NCT07238075 ↗

Phase 1 Recruiting 290 enrolled Adcytherix SAS
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this first-in-human study is to explore the safety, pharmacokinetics and effects of the study drug ADCX-020 in patients with advanced and metastatic solid tumors. ADCX-020 is an investigational anticancer therapy called antibody drug conjugate. This study is set up in multiple parts. In the first part of the study, participants receive increasing doses of ADCX-020. Then 2 or more doses will be assessed to identify the optimal dose. This optimal dose is subsequently evaluated for effect on different cancer types.

Timeline

Start
2026-02-23
Primary completion
2029-07-31
Completion
2029-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject ADCX-020 Other / unclassified — Intravenous