drugset / Trial / NCT07241338
Sacubitril/Allisartan for Hypertensive Patients With Overweight or Obesity
RandomizedParallel-groupOpen-labelTreatment
Summary
To compare the efficacy and safety of sacubitril/Allisartan versus amlodipine in the antihypertensive treatment of overweight/obese patients with primary hypertension
Timeline
- Start
- 2025-11
- Primary completion
- 2026-11
- Completion
- 2027-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amlodipine | Other / unclassified | 5 mg | Oral |
| Comparator | Amlodipine | Other / unclassified | 10 mg | Oral |
| Subject | Sacubitril | Small molecule | 240 mg | Oral |
| Subject | Sacubitril | Small molecule | 480 mg | Oral |