drugset / Trial / NCT07242222
Erdosteine in the Treatment of Nonalcoholic Fatty Liver Disease
RandomizedParallel-groupDouble-blindTreatment
Summary
Nonalcoholic fatty liver disease (NAFLD) is a global public health concern, and the leading cause of chronic liver disease, especially in developed countries (1). NAFLD is characterized by lipid accumulation in the liver not attributed to other causes. NAFLD is characterized by excessive hepatic fat accumulation without other recognized causes of increased fat content (e.g., alcohol, virus, drugs, and autoimmunity). According to the Clinical Practice Guidelines of the European Association for the Study of the Liver, the diagnosis of NAFLD requires the exclusion of daily alcohol consumption \>30 g for men and \>20 g for women
Timeline
- Start
- 2025-11-20
- Primary completion
- 2026-11-20
- Completion
- 2026-11-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Erdosteine | Small molecule | 300 mg | Oral |