drugset / Trial / NCT07245771
Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity
Phase 1/2
Recruiting
104 enrolled
Ikaria Bioscience Pty Ltd
Shanghai Rona Therapeutics Co., Ltd. · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Study to assess the safety, pharmacokinetics (the amount of study drug or any of its breakdown products in your body) and pharmacodynamics (how the study drug affects your body) of RN3161 alone (healthy volunteers) and RN3161 with tirzepatide (overweight and obese subjects)
Timeline
- Start
- 2025-11-04
- Primary completion
- 2027-02-15
- Completion
- 2027-08-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | RN3161 | Unknown | — | — |
| Background | Tirzepatide | Peptide | — | — |