drugset / Trial / NCT07247162

Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome

NCT07247162

Phase 4 Not yet recruiting 63 enrolled RECORDATI GROUP
RandomizedParallel-groupTriple-blindTreatment

Summary

Osilodrostat has proven to be a safe and efficacious treatment for patients with CS. Demonstrating normalisation of hypercortisolaemia and in patients with hypertension and/or dysglycaemia clinically relevant and statistically significant reductions in blood pressure and glycaemia. This study aims at providing additional evidence on the safety, efficacy and appropriate dosing of osilodrostat in patients with CS, who have hypertension.

Timeline

Start
2026-08
Primary completion
2028-05
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject osilodrostat Small molecule 1 mg Oral
Subject osilodrostat Small molecule 5 mg Oral