drugset / Trial / NCT07247240
Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia
Phase 4
Not yet recruiting
40 enrolled
Asan Medical Center
Chungnam National University Hospital · collabSeoul National University Hospital · collabSeverance Hospital · collab
NaSingle-groupOpen-labelTreatment
Summary
This multicenter, prospective, single-arm study aims to evaluate the efficacy of inhaled nitric oxide (iNO) in neonates with congenital diaphragmatic hernia (CDH) and early pulmonary hypertension. Short-term treatment response will be assessed by the changes in oxygenation index and other parameters including echocardiographic parameters at predefined intervals.
Timeline
- Start
- 2025-11
- Primary completion
- 2028-12
- Completion
- 2028-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nitric Oxide | Other / unclassified | 20 ppm | Inhaled |