drugset / Trial / NCT07247370
Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL)
Phase 1/2
Not yet recruiting
20 enrolled
South West Sydney Local Health District
University of Sydney · collab
NaSingle-groupOpen-labelTreatment
Summary
To assess the safety, feasibility and preliminary efficacy of ketamine-enhanced therapy (KET) for alcohol use disorder (AUD) and comorbid major depressive disorder (MDD) in an open-label, single arm, pilot clinical trial.
Timeline
- Start
- 2025-12-10
- Primary completion
- 2027-04-10
- Completion
- 2027-12-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 0.7 mg/kg | Subcutaneous |
| Subject | Ketamine | Small molecule | 1.2 mg/kg | Subcutaneous |