drugset / Trial / NCT07253246

ENX-205 SAD/PET Study in Healthy Adults

NCT07253246 ↗

Phase 1 Completed 59 enrolled Engrail Therapeutics INC
RandomizedParallel-groupTriple-blindOther

Summary

This is a two-part study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and receptor occupancy (RO) of ENX-205 in healthy adult participants in a double-blind placebo-controlled, single ascending dose (SAD) study (Part 1) and an open-label, single-dose, positron emission tomography (PET) study (Part 2).

Timeline

Start
2025-03-23
Primary completion
2026-05-07
Completion
2026-05-07

Drugs

EvaluationDrugModalityDoseRoute
Subject ENX-205 Unknown — Oral

Indications

No indication recorded.