drugset / Trial / NCT07254715

Effect of Itopride on Semaglutide Gastroparesis

NCT07254715

Phase 4 Recruiting 60 enrolled Ain Shams University
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Semaglutide delays gastric emptying and increases the risk of aspiration with anesthesia; So, the addition of prokinetics as Itopride, could enhance gastric emptying and hasten surgery. The investigator will evaluate the effect of Itopride on Semaglutide-induced gastroparesis and residual gastric contents after 8 hours of fasting by gastric ultrasound before anesthesia.

Timeline

Start
2025-12
Primary completion
2026-04
Completion
2026-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Itopride Small molecule 50 mg Oral

Indications

No indication recorded.