A Study Of Opioid Avoidance In Surgery Through Integrating Suzetrigine

Phase 4 Completed 100 enrolled Mayo Clinic

NaSingle-groupOpen-labelOther

Summary

This prospective, single-arm feasibility study will evaluate postoperative pain control, opioid use, and early recovery outcomes in adult patients undergoing elective outpatient facial plastic surgery who receive suzetrigine as part of their standard postoperative analgesic regimen.

Timeline

Start: 2025-10-20
Primary completion: 2026-03-01
Completion: 2026-04-01

Publications

Valencia-Sanchez BA, Colontonio MM, Menapace DC. Protocol for a prospective single-arm feasibility study of suzetrigine for postoperative pain management in outpatient facial plastic surgery. Pain Manag. 2026 May 19:1-6. doi: 10.1080/17581869.2026.2676101. Online ahead of print.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Suzetrigine	Small molecule	50 mg	Oral

Indications

No indication recorded.