drugset / Trial / NCT07264010

Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical Study

NCT07264010

Phase 2/3 Not yet recruiting 87 enrolled Nanfang Hospital, Southern Medical University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to explore the efficacy and safety of sorafenib combined with venetoclax as pre-emptive therapy strategy for measurable residual disease persisting acute myeloid leukemia.

Timeline

Start
2025-12-01
Primary completion
2026-12-30
Completion
2028-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 400 mg
Subject Venetoclax Small molecule 400 mg