drugset / Trial / NCT07264569
Evaluate the Safety, Tolerability, Biodistribution Characteristics and Preliminary Efficacy of BioTTT001
NaSingle-groupOpen-labelTreatment
Summary
Phase Ib/II clinical study on evaluating the safety, tolerance, biodistribution characteristics and preliminary efficacy of recombinant human nsIL12 oncolytic adenovirus injection (BioTT001) in the treatment of meningeal metastasis in recurrent/progressive non-small cell lung cancer
Timeline
- Start
- 2025-06-25
- Primary completion
- 2027-12-30
- Completion
- 2027-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BioTTT001 | Unknown | 1e+09 vg | Intrathecal |
| Subject | BioTTT001 | Unknown | 5e+09 vg | Intrathecal |
| Subject | BioTTT001 | Unknown | 1e+10 vg | Intrathecal |