drugset / Trial / NCT07266948

Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work

NCT07266948 ↗

Phase 4 Recruiting 40 enrolled Southern College of Optometry
NaSingle-groupOpen-labelTreatment

Summary

This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina (Minneapolis, MN). Adults ≥18 years of age who have been diagnosed with DED for at least 6 months and who are currently symptomatic (Eye Dryness VAS Score ≥40) will be recruited. Subjects will have an abnormal Schirmer test of \<10 mm/5 min. Subjects will also be required to score ≤70 on the IDEEL Quality of Life (QoL) Work domain to ensure that their DED symptoms are significantly impacting their ability to do work.9 Subjects will be required to have corrected distance visual acuity of 20/32 (0.2 logMAR) or better.

Timeline

Start
2025-11-01
Primary completion
2026-01-31
Completion
2026-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Acoltremon Small molecule 0.003 % —

Indications