drugset / Trial / NCT07271667

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

NCT07271667

Phase 2 Recruiting 108 enrolled Curis, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

The primary objective of the study for Cohort 1 and Cohort 2 is to assess the anticancer activity of emavusertib in combination with zanubrutinib in participants with CLL.

Timeline

Start
2026-04-23
Primary completion
2027-11
Completion
2027-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Emavusertib Small molecule Oral
Background Zanubrutinib Small molecule Oral