Use of Subanesthetic Dose Propofol Before Extubation

Summary

This study investigates whether administering a low, sub-anesthetic dose of propofol before extubation can reduce emergence agitation and improve perioperative comfort in patients undergoing rhinoplasty. Emergence agitation refers to restlessness and confusion during early recovery from anesthesia, which may affect patient safety and surgical conditions. The study evaluates agitation levels, recovery characteristics, and patient-reported comfort following propofol administration compared with standard care.

Timeline

Start

2024-06-01

Primary completion

2024-09-01

Completion

2024-10-01

Publications

• Background Kanaya A, Kuratani N, Satoh D, Kurosawa S. Lower incidence of emergence agitation in children after propofol anesthesia compared with sevoflurane: a meta-analysis of randomized controlled trials. J Anesth. 2014 Feb;28(1):4-11. doi: 10.1007/s00540-013-1656-y. Epub 2013 Jun 26.
• Izmir E, Yuzkat N, Kiyat H, Tekeli AE, Gunes HY, Kurt N, Keskin ME. Effect of a subanesthetic dose of propofol on emergence agitation in adults undergoing rhinoplasty: A prospective randomized controlled trial. Medicine (Baltimore). 2026 Jul 10;105(28):e49693. doi: 10.1097/MD.0000000000049693.

Drugs

Indications

No indication recorded.