drugset / Trial / NCT07286370

A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella Disease and Typhoid Fever in Infants

NCT07286370

Phase 2 Recruiting 537 enrolled GlaxoSmithKline
RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this study is to evaluate the safety, reactogenicity, and immune response induced by the GlaxoSmithKline Biologicals SA (GSK) Vaccines Institute for Global Health (GVGH) invasive nontyphoidal Salmonella-typhoid conjugate (iNTS-TCV) vaccine in infants with the first dose administered at 6 months of age (MOA) or 6 weeks of age (WOA).

Timeline

Start
2026-04-01
Primary completion
2028-04-27
Completion
2028-04-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Menveo Vaccine
Subject Prevnar 13 Vaccine
Comparator TYPHIBEV Vaccine
Subject iNTS-TCV Vaccine

Indications