drugset / Trial / NCT07288190
Phase 2b, Open Label, Multisite, Randomized Crossover Study of DPP Versus 2PR
Phase 2
Not yet recruiting
300 enrolled
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID) · collab
RandomizedCrossoverOpen-labelPrevention
Summary
To evaluate adherence to a single dual-prevention pill (DPP) compared with a two-pill regimen (2PR) for pre-exposure prophylaxis (PrEP) and pregnancy prevention in women without HIV.
Timeline
- Start
- 2026-05-15
- Primary completion
- 2028-05-15
- Completion
- 2028-05-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Levonorgestrel | Small molecule | — | Oral |
| Background | Tenofovir disoproxil fumarate | Small molecule | — | Oral |
| Background | emtricitabine | Other / unclassified | — | Oral |
| Background | ethinyl estradiol | Small molecule | — | Oral |