drugset / Trial / NCT07293351

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

NCT07293351 ↗

Phase 1/2 Recruiting 474 enrolled Bristol-Myers Squibb BioNTech SE · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, and efficacy of Pumitamig alone or in combination with other agents in participants with advanced Renal Cell Carcinoma (RCC)

Timeline

Start
2026-03-26
Primary completion
2029-11-28
Completion
2031-11-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule — —
Subject Casdatifan Small molecule — —
Subject Ipilimumab Monoclonal antibody — —
Subject Pumitamig Protein / enzyme biologic — —

Indications