drugset / Trial / NCT07294508

A Study to Evaluate HLX22 in Combination With HLX87 in Patients With HER2-Positive Recurrent or Metastatic Breast Cancer

NCT07294508

Phase 2/3 Recruiting 706 enrolled Shanghai Henlius Biotech
RandomizedParallel-groupOpen-labelTreatment

Summary

The study is being conducted to evaluate the clinical efficacy of HLX22 in combination with HLX87 as first-line treatment in patients with HER2-positive recurrent or metastatic breast cancer

Timeline

Start
2026-02-27
Primary completion
2028-01-15
Completion
2030-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Docetaxel Small molecule
Subject HLX22 Monoclonal antibody
Subject HLX87 Other / unclassified
Subject Pertuzumab Monoclonal antibody
Comparator T-Dxd Unknown
Comparator Trastuzumab Monoclonal antibody