drugset / Trial / NCT07295821

Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study

NCT07295821

Phase 2 Recruiting 60 enrolled AstraZeneca
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to measure efficacy and safety of osimertinib as induction therapy prior to curative intent RT and maintenance osimertinib in chemotherapy ineligible or refusal adult patients with Stage III, unresectable NSCLC with common EGFR mutations (exon 19 deletion or L858R).

Timeline

Start
2026-04-01
Primary completion
2029-05-30
Completion
2029-05-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Osimertinib Small molecule 80 mg

Indications