drugset / Trial / NCT07295951

A Study of 14C-Bleximenib (Radiolabeled) in Participants With Acute Leukemia

NCT07295951

Phase 1 Recruiting 10 enrolled Janssen Research & Development, LLC
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess how the body absorbs, breaks down (metabolism), and removes (excretes) radiolabeled bleximenib (a drug molecule that has been chemically bonded with a radioactive isotope which emits radiation making it easier to track in the body) in participants with acute leukemia (highly aggressive blood cancer typically characterized by large numbers of immature white blood cells in the bone marrow).

Timeline

Start
2025-11-18
Primary completion
2026-06-14
Completion
2026-07-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Bleximenib Small molecule Oral