Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

Summary

This study aims to determine the safety and preliminary efficacy of psilocybin-assisted psychotherapy in improving alcohol-related outcomes among adults with severe alcohol use disorder in a a double-blind, dose-comparison concurrent control, randomized trial. Participants will undergo structured psychotherapy and will be randomized to two psilocybin sessions to receive either a full dose (30mg or 40mg) or low dose (10mg or 15mg).

Timeline

Start

2026-06-15

Primary completion

2029-12-01

Completion

2030-02

Drugs

Indications