drugset / Trial / NCT07296614
Clinical Evaluation of Integrated Chinese-Western Medicine for Infertility With DOR Patients in Women Achieving Natural Pregnancy
Phase 3
Not yet recruiting
320 enrolled
Peking Union Medical College Hospital
Affiliated Hospital of Shandong University of Traditional Chinese Medicine · collabBeijing Obstetrics and Gynecology Hospital · collabBeijing University of Chinese Medicine · collabDongfang Hospital Beijing University of Chinese Medicine · collabFirst Affiliated Hospital of Heilongjiang Chinese Medicine University · collabGuangdong Provincial Hospital of Traditional Chinese Medicine · collabHunan Provincial Maternal and Child Health Care Hospital · collabInstitute of Basic Medical Sciences CAMS · collabShandong University · collabShenyang Women's and Children's Hospital · collabShunde Women and Children's Hospital (Maternity and Child Healthcare Hospital of Shunde Foshan) · collabThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · collabThe First Affiliated Hospital of Hunan University of Traditional Chinese Medicine · collabThe First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine · collabThe First Affiliated Hospital of Zhengzhou University · collabThe Third Affiliated Hospital of Beijing University of Chinese Medicine · collabXiamen University · collabXiyuan Hospital of China Academy of Chinese Medical Sciences · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study aims to evaluate the superiority of an integrated traditional Chinese and Western medicine regimen ("Xiehe DOR Bushen Tongzhi Formula" + ovulation induction therapy with ovulation monitoring and timed intercourse) compared to standard treatment alone (placebo + ovulation induction therapy with ovulation monitoring and timed intercourse) in improving the natural cumulative clinical pregnancy rate in infertile patients with kidney deficiency-type diminished ovarian reserve (DOR).
Timeline
- Start
- 2025-12-25
- Primary completion
- 2028-07-30
- Completion
- 2028-07-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Xiehe DOR Kidney-Tonifying Universal Formula | Traditional medicine (herbal / TCM) | — | Oral |
| Background | Letrozole | Other / unclassified | 2.5 mg | Oral |